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Manhattan, 1996. All mental hospitals must cut their patient load by a third, and LaRue (Will Keenan) is sent out onto the streets with "chronic reading syndrome". He ends up at the Love Hotel (where most of the inmates are being held), and falls in love with a mute girl who's obsessive mother dominates her life. To top it all off, LaRue is given a roommate with Tourette's syndrome and is chased by a prehistoric worm that inhabits peoples bodies and mutates them.